Humanin, a mitochondrial-derived peptide, has gained interest among researchers for its potential benefits in mitochondrial health and longevity. While scientific studies are ongoing, some self-experimenters have shared their experiences with various dosing protocols. Here’s an overview of anecdotal reports on Humanin dosing.
Dosage Range
The dosage range for Humanin varies widely in anecdotal reports. One Reddit user mentioned that the theoretical dosage they found was 25-50μg daily. However, it’s important to note that optimal dosing can vary between individuals and depends on the specific form of Humanin used.
Humanin vs. Humanin G
Some researchers suggest that Humanin G, a more potent variant, might be preferable due to its altered potency. However, specific dosing recommendations for Humanin G are not well-established in these anecdotal reports.
Frequency of Administration
Dosing frequency varies among users. One experimenter reported using 5mg of Humanin once per week, typically on Wednesdays. This was part of a regimen that also included MOTS-C on Mondays and Fridays.
Stability Concerns
A significant concern among users is the stability of Humanin in solution. One Reddit discussion highlighted the challenge of reconstituting large amounts at once, given the small dosages typically used. Some users suggested using syringe filters to maintain sterility when dividing doses.
Combination with Other Peptides
Some researchers combine Humanin with other mitochondrial peptides. A protocol shared on Reddit described a “Fitness Protocol” that combined NAD, MOTS-C, and Humanin for mitochondrial enhancement, with subcutaneous injections 5 out of 7 days per week in the morning.
Safety Considerations
It’s crucial to note that some researchers express concerns about potential side effects, particularly regarding STAT3 activation. The short half-life of Humanin may mitigate some risks, but long-term safety data is lacking.
Conclusion
While these anecdotal reports provide interesting insights into how some researchers are experimenting with Humanin, it’s important to emphasize that these are not scientifically validated protocols. The optimal dosage, timing, and duration for human use remain unknown. Anyone considering Humanin use should approach it with caution and ideally under professional guidance.
